pentobarbital will lower the level or outcome of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can lessen panobinostat degrees by ~70% and bring on r